A study comparing Biothera’s Wellmune to other forms of beta glucans was published in an April 2011 edition of the journal Nature. The researchers tested the ability of several different forms of beta glucans to activate Dectin-1, a key receptor that primes immune cells to defend against foreign elements. They found that Wellmune activated Dectin-1 while other soluble forms of beta glucans did not. This study demonstrates that the structure of beta glucans is important in supporting the immune system, and that Wellmune’s structure is suited to do just that.
Goodridge HS, Reyes CN, Becker CA, Katsumoto TR, Ma J, Wolf AJ, Bose N, Chan ASH, Magee AS, Danielson ME, Weiss A, Vasilakos JP, Underhill DM. Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse.’ Nature 2011; 472: 471-476.
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